FPR3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA297988-50UL
100 ul
£334.00
CSB-PA297988-100UL
About this Product
- SKU:
- CSB-PA297988
- Additional Names:
- FML2_HUMAN antibody; FMLP related receptor II antibody; FMLP-R-II antibody; FMLP-related receptor II antibody; FMLPY antibody; Formyl peptide receptor 3 antibody; Formyl peptide receptor like 2 antibody; Formyl peptide receptor-like 2 antibody; FPR3 antibody; FPR3_HUMAN antibody; FPRH1 antibody; FPRH2 antibody; FPRL2 antibody; Lipoxin A4 receptor antibody; LXA4 R antibody; Lxa4r antibody; N formyl peptide receptor 3 antibody; N-formyl peptide receptor 3 antibody; RGD1566044 antibody; RMLP-R-I antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- The N-formyl peptide receptor (FPR) family is comprised of three members, FPR, FPR3 (also designated FPRL1, lipoxin A4 receptor, FPRH1 or FPR2) and FPR like-2 (FPRL2), all of which are chemotactic G protein-coupled receptors that contain seven transmembrane domains. These receptors are found on the surface of phagocytic leukocytes, such as neutrophils and monocytes, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR3 is a promiscuous receptor that binds to several ligands, including lipoxin A4, N-formyl-methionyl-leucyl-phenylalanine (fMLP), serum amyloid A (SAA), prion peptide and the 42 amino acid form of beta amyloid. Upon activation, FPR3 induces migration and calcium mobilization in human monocytes and neutrophils and is involved in inflammatory and host defense responses. FPR3 may mediate inflammation in prion and Alzheimer's diseases, which makes it a potential target for therapeutic agents.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human FPR3
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:FPR3-Antibody-11104735.html
