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Antibodies

INS Antibody

Product Sizes
50 ul
£186.00
CSB-PA285156-50UL
100 ul
£334.00
CSB-PA285156-100UL
About this Product
SKU:
CSB-PA285156
Additional Names:
IDDM 2 antibody; IDDM2 antibody; ILPR antibody; ins antibody; INS_HUMAN antibody; Insulin A chain antibody; IRDN antibody; MODY10 antibody; Proinsulin antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human INS
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA285156(INS Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA285156(INS Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)