IQGAP3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA283992-50UL
100 ul
£334.00
CSB-PA283992-100UL
About this Product
- SKU:
- CSB-PA283992
- Additional Names:
- IQ motif containing GTPase activating protein 3 antibody; IQGA3_HUMAN antibody; IQGAP 3 antibody; IQGAP3 antibody; MGC10170 antibody; MGC10831 antibody; MGC1947 antibody; OTTHUMP00000031854 antibody; OTTHUMP00000031855 antibody; Ras GTPase activating like protein IQGAP3 antibody; Ras GTPase-activating-like protein IQGAP3 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human IQGAP3
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Rabbit-anti-human-IQGAP3-polyclonal-antibody-11099630.html
