NACC1 Antibody
Product Sizes
100 ul
£332.00
CSB-PA283286-100UL
About this Product
- SKU:
- CSB-PA283286
- Additional Names:
- BEND8 antibody; BTB Domain Containing 14B antibody; BTB/POZ domain-containing protein 14B antibody; btbd14b antibody; FLJ37383 antibody; NAC-1 antibody; NAC1 antibody; Nacc1 antibody; NACC1_HUMAN antibody; Nucleus accumbens-associated protein 1 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival." Nakayama K., Nakayama N., Davidson B.,et al. Proc. Natl. Acad. Sci. U.S.A. 103:18739-18744(2006) "NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor." Nakayama K., Nakayama N., Wang T.-L., Shih I.-M. Cancer Res. 67:8058-8064(2007)
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.519~523(A-G-P-S-A) derived from Human NAC1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NACC1-Antibody-11083350.html
