PIAS3 Antibody
Product Sizes
100 ul
£332.00
CSB-PA283252-100UL
About this Product
- SKU:
- CSB-PA283252
- Additional Names:
- E3 SUMO protein ligase PIAS 3 antibody; E3 SUMO protein ligase PIAS3 antibody; E3 SUMO-protein ligase PIAS3 antibody; FLJ14651 antibody; OTTHUMP00000015586 antibody; OTTHUMP00000015587 antibody; PIAS 3 antibody; Pias3 antibody; PIAS3 protein antibody; PIAS3_HUMAN antibody; Protein inhibitor of activated STAT 3 antibody; Protein inhibitor of activated STAT protein 3 antibody; Protein inhibitor of activated STAT3 antibody; Zinc finger MIZ type containing 5 antibody; ZMIZ 5 antibody; ZMIZ5 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566. Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592. Jianyin Long, PNAS, Jan 2004; 101: 99. Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Internal of Human PIAS3.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PIAS3-Antibody-11084694.html
