EPHB4 Antibody
Product Sizes
100 ul
£332.00
CSB-PA277115-100UL
About this Product
- SKU:
- CSB-PA277115
- Additional Names:
- Ephb4 antibody; EPHB4_HUMAN antibody; Ephrin receptor EphB4 antibody; Ephrin type-B receptor 4 antibody; Hepatoma Transmembrane Kinase antibody; HTK antibody; MYK 1 antibody; MYK1 antibody; TYRO 11 antibody; TYRO11 antibody; Tyrosine-protein kinase receptor HTK antibody; Tyrosine-protein kinase TYRO11 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. Bennett B.D., J. Biol. Chem. 269:14211-14218(1994). Wilson M.D., Nucleic Acids Res. 29:1352-1365(2001). Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human EPHB4.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:EPHB4-Antibody-11085004.html
