FOXK1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA275426-50UL
100 ul
£334.00
CSB-PA275426-100UL
About this Product
- SKU:
- CSB-PA275426
- Additional Names:
- A630048H08Rik antibody; AI463295 antibody; ENSMUSG00000075577 antibody; FHX antibody; Fork head antibody; Forkhead box protein K1 antibody; FOXJ2 forkhead factor antibody; FOXK1 antibody; FOXK1_HUMAN antibody; Gm10868 antibody; MNF antibody; Myocyte nuclear factor antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human FOXK1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:FOXK1-Antibody-11102953.html
