GZMB Antibody
Product Sizes
100 ul
£332.00
CSB-PA272248-100UL
About this Product
- SKU:
- CSB-PA272248
- Additional Names:
- C11 antibody; Cathepsin G like 1 antibody; Cathepsin G-like 1 antibody; CCPI antibody; CGL 1 antibody; CGL1 antibody; CSP B antibody; CSPB antibody; CTLA 1 antibody; CTLA-1 antibody; CTLA1 antibody; CTSGL1 antibody; Cytotoxic serine protease B antibody; Cytotoxic T lymphocyte associated serine esterase 1 antibody; Cytotoxic T lymphocyte proteinase 2 antibody; Cytotoxic T-lymphocyte proteinase 2 antibody; Fragmentin 2 antibody; Fragmentin-2 antibody; GRAB_HUMAN antibody; Granzyme 2 antibody; Granzyme B (granzyme 2; cytotoxic T lymphocyte associated serine esterase 1) antibody; Granzyme B antibody; Granzyme-2 antibody; GranzymeB antibody; GRB antibody; Gzmb antibody; Hlp antibody; Human lymphocyte protein antibody; Lymphocyte protease antibody; Protease; serine; B antibody; SECT antibody; T cell serine protease 1 3E antibody; T cell serine protease 1-3E antibody; T-cell serine protease 1-3E antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. David A. Jans, J. Biol. Chem., Nov 1996; 271: 30781. Eugene Estella, Diabetes, Aug 2006; 55: 2212 - 2219. Yong Gu, J. Biol. Chem., May 1996; 271: 10816. Jiuru Sun, J. Biol. Chem., Nov 1996; 271: 27802.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human Granzyme B.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GZMB-Antibody-11084568.html
