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Antibodies

EP300/CREBBP Antibody

Product Sizes
100 ul
£332.00
CSB-PA265859-100UL
About this Product
SKU:
CSB-PA265859
Additional Names:
E1A associated protein p300 antibody; E1A binding protein p300 antibody; E1A-associated protein p300 antibody; EP300 antibody; EP300: E1A binding protein p300 antibody; EP300_HUMAN antibody; Histone acetyltransferase p300 antibody; KAT3B antibody; p300 HAT antibody; RSTS2 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Gerd A. Blobel, J. Leukoc. Biol., Apr 2002; 71: 545. Eric Kalkhoven, Hum. Mol. Genet., Feb 2003; 12: 441 - 450. Wei-fang Shen, Mol. Cell. Biol., Nov 2001; 21: 7509 - 7522. Frederick C. Nucifora, Science, Mar 2001; 291: 2423.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from Human P300/CBP.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody