NRG3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA262646-50UL
100 ul
£334.00
CSB-PA262646-100UL
About this Product
- SKU:
- CSB-PA262646
- Additional Names:
- HRG3 antibody; Neuregulin 3 antibody; Neuregulin 3 like polypeptide antibody; Neuregulin-3 antibody; Neuregulin3 antibody; NRG-3 antibody; Nrg3 antibody; NRG3_HUMAN antibody; Pro neuregulin 3 antibody; pro NRG3 antibody; Pro-NRG3 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human NRG3
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NRG3-Antibody-11104253.html
