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Antibodies

IRS1 (Ab-636) Antibody

Product Sizes
100 ul
£332.00
CSB-PA259956-100UL
About this Product
SKU:
CSB-PA259956
Additional Names:
HIRS 1 antibody; HIRS1 antibody; Insulin receptor substrate 1 antibody; IRS 1 antibody; IRS-1 antibody; IRS1 antibody; IRS1_HUMAN antibody; OTTHUMP00000164234 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645 Tzatsos A, et al. (2006) Mol Cell Biol; 26(1): 63-76 Kadowaki T, et al. (2000) J Clin Invest; 106(4): 459-465 Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645 Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97(5): 2355-2360
Host:
Rabbit
Immunogen:
Peptide sequence around aa.634~638 (P-M-S-P-K) derived from Human IRS-1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody