GAD2 Antibody
Product Sizes
100 ul
£332.00
CSB-PA258867-100UL
About this Product
- SKU:
- CSB-PA258867
- Additional Names:
- Glutamate decarboxylase 2; EC 4.1.1.15; Glutamate decarboxylase 65 kDa isoform; GAD-65; 65 kDa glutamic acid decarboxylase
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. JB Travers, Chem Senses, Feb 2007; 32: 129 - 137. Rita Sulahian, Nucleic Acids Res., Mar 2006; 34: 1351 - 1357. Andrea Pillai, Development, Jan 2007; 134: 357 - 366. Dmytro P. Yevtushenko, J. Exp. Bot., Aug 2003; 54: 2001 - 2002.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human GAD1/GAD2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GAD2-Antibody-11084555.html
