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Antibodies

MITF (Ab-180/73) Antibody

Product Sizes
100 ul
£332.00
CSB-PA257242-100UL
About this Product
SKU:
CSB-PA257242
Additional Names:
BHLHE32 antibody; bHLHe32 antibody; Class E basic helix-loop-helix protein 32 antibody; CMM8 antibody; Homolog of mouse microphthalmia antibody; Mi antibody; Microphthalmia associated transcription factor antibody; Microphthalmia, mouse, homolog of antibody; Microphthalmia-associated transcription factor antibody; MITF antibody; MITF_HUMAN antibody; mitfa antibody; nacre antibody; WS2 antibody; WS2A antibody; z3A.1 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. J
Host:
Rabbit
Immunogen:
Synthesized non-phosphopeptide derived from Human MITF around the phosphorylation site of serine 180/73 (P-N-S(p)-P-M).
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody