F10 Antibody
Product Sizes
50 ul
£186.00
CSB-PA245689-50UL
100 ul
£334.00
CSB-PA245689-100UL
About this Product
- SKU:
- CSB-PA245689
- Additional Names:
- Activated factor Xa heavy chain antibody; Coagulation factor X antibody; F10 antibody; FA10_HUMAN antibody; FX antibody; FXA antibody; Prothrombinase antibody; Stuart factor antibody; Stuart Prower factor antibody; Stuart-Prower factor antibody
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human F10
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:F10-Antibody-11100143.html
