MCM3AP Antibody
Product Sizes
100 ul
£332.00
CSB-PA243490-100UL
About this Product
- SKU:
- CSB-PA243490
- Additional Names:
- 80 kDa MCM3 associated protein antibody; 80 kDa MCM3-associated protein antibody; FLJ44336 antibody; FLJ45306 antibody; Germinal center associated nuclear protein antibody; KIAA0572 antibody; MAP80 antibody; MCM3 import protein antibody; MCM3 minichromosome maintenance deficient 3 associated protein antibody; MCM3A antibody; MCM3A_HUMAN antibody; Mcm3ap antibody; Minichromosome maintenance complex component 3 associated protein antibody; Minichromosome maintenance deficient 3 associated protein antibody; Minichromosome maintenance protein 3 associated protein antibody; Protein GANP antibody; SAC3 antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Isoform GANP:Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells By similarity. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Isoform MCM3AP:Acetyltransferase targeting MCM3. Inhibits initiation of DNA replication, but not elongation. Nobuo Sakaguchi, J. Immunol., Apr 2005; 174: 4485 - 4494. Kazuhiko Kuwahara, Blood, Apr 2000; 95: 2321 - 2328. Y Kono, K Maeda, Genes Cells, Aug 2002; 7: 821 - 834. Kazuhiko Kuwahara, PNAS, Aug 2001; 98: 10279.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human GANP.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MCM3AP-Antibody-11084557.html
