FOXO1 (Ab-256) Antibody
Product Sizes
100 ul
£332.00
CSB-PA228665-100UL
About this Product
- SKU:
- CSB-PA228665
- Additional Names:
- FKH 1 antibody; FKH1 antibody; FKHR antibody; Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody; Forkhead box O1 antibody; Forkhead box protein O1 antibody; Forkhead box protein O1A antibody; Forkhead in rhabdomyosarcoma antibody; Forkhead; Drosophila; homolog of; in rhabdomyosarcoma antibody; FoxO transcription factor antibody; foxo1 antibody; FOXO1_HUMAN antibody; FOXO1A antibody; OTTHUMP00000018301 antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14 Gan L, et al. (2005) J Neurochem; 93(5): 1209-19. Smith WW, et al. (2005) J Cell Biol; 169(2): 331-9. Di Maira G, et al. (2005) Cell Death Differ; 12(6): 668-77. Horn S, et al. (2004) Leukemia; 18(11): 1839-49. Zhao X, et al. (2004) Biochem J 4; 378(Pt 3): 839-49.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.254~258 (A-A-S-M-D) derived from Human FKHR/FOXO1A.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:FOXO1-Ab-256-Antibody-11083002.html
