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Antibodies

BFAR Antibody

Product Sizes
50 ul
£186.00
CSB-PA217827-50UL
100 ul
£334.00
CSB-PA217827-100UL
About this Product
SKU:
CSB-PA217827
Additional Names:
BFAR antibody; BAR antibody; RNF47Bifunctional apoptosis regulator antibody; RING finger protein 47 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
A novel protein, BAR, for bifunctional apoptosis regulator, contains domains that enable it to interact with components of both major apoptosis pathways, where it negatively regulates apoptotic signaling. Like the other anti-apoptosis proteins Bap31 and FLIP, BAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. In addition, BAR contains a domain that also enables it to interact with the mitochondrial Bcl-2 family of proteins. The presence of these various RING, SAM, DED and TM domains suggests that BAR may serve as a scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human BFAR
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA217827(BFAR Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA217827(BFAR Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)