GRK6 Antibody
Product Sizes
100 ul
£332.00
CSB-PA213352-100UL
About this Product
- SKU:
- CSB-PA213352
- Additional Names:
- FLJ32135 antibody; G protein coupled receptor kinase 6 antibody; G protein coupled receptor kinase GRK6 antibody; G protein-coupled receptor kinase 6 antibody; G protein-coupled receptor kinase GRK6 antibody; Gprk6 antibody; Grk6 antibody; GRK6_HUMAN antibody
- Application:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). Benovic J.L., J. Biol. Chem. 268:19521-19527(1993). Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993). Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from N-terminal of Human GRK6.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GRK6-Antibody-11084955.html
