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Antibodies

NRG1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA211518-100UL
About this Product
SKU:
CSB-PA211518
Additional Names:
Pro-neuregulin-1; membrane-bound isoform; Pro-NRG1; NRG1; GGF
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). Xiao-Feng Le, Cancer Res., Jul 2000; 60: 3522 - 3531. Samuel D. H. Chan, J. Biol. Chem., Sep 1995; 270: 22608. Daniel C. Gamett, J. Biol. Chem., Aug 1995; 270: 19022. Mohammed Rahmatullah, Mol. Cell. Biol., Nov 1998; 18: 6245 - 6252.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from Human NRG1 isoform-10.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody