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Antibodies

DUSP10 Antibody

Product Sizes
50 ul
£186.00
CSB-PA207957-50UL
100 ul
£334.00
CSB-PA207957-100UL
About this Product
SKU:
CSB-PA207957
Additional Names:
Dual specificity phosphatase 10 antibody; Dual specificity phosphatase MKP 5 antibody; Dual specificity phosphatase MKP5 antibody; Dual specificity protein phosphatase 10 antibody; DUS10_HUMAN antibody; DUSP 10 antibody; DUSP10 antibody; DUSP10 protein antibody; MAP kinase phosphatase 5 antibody; Mitogen activated protein kinase phosphatase 5 antibody; Mitogen-activated protein kinase phosphatase 5 antibody; MKP 5 antibody; MKP-5 antibody; MKP5 antibody; Serine/threonine specific protein phosphatase antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus.
Host:
Rabbit
Immunogen:
Fusion protein of Human DUSP10
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody