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Antibodies

KSR1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA202913-50UL
100 ul
£334.00
CSB-PA202913-100UL
About this Product
SKU:
CSB-PA202913
Additional Names:
BKSR 1 antibody; BKSR1 antibody; dKsr antibody; EK 31 antibody; EK31 antibody; hb antibody; Kinase suppressor of Ras 1 antibody; Kinase suppressor of ras antibody; KSR 1 antibody; KSR antibody; KSR1 antibody; KSR1_HUMAN antibody; Positive Ras signaling mediator family member (86.4 kD) antibody; Positive Ras signaling mediator family member antibody; RSU 2 antibody; RSU2 antibody; SR 31 antibody; SR31 antibody; Suppressor of activated let 60 Ras SUR3 antibody; Suppressor of Ras1 31 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGF -activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGF stimulation.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human KSR1
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody