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Antibodies

MMP25 Antibody

Product Sizes
50 ul
£186.00
CSB-PA198245-50UL
100 ul
£334.00
CSB-PA198245-100UL
About this Product
SKU:
CSB-PA198245
Additional Names:
Leukolysin antibody; matrix metallopeptidase 25 antibody; matrix metallopeptidase like 1 antibody; matrix metalloproteinase 20 antibody; Matrix Metalloproteinase 25 antibody; Matrix metalloproteinase 25 precursor antibody; Matrix metalloproteinase-25 antibody; Membrane type 6 Matrix Metalloproteinase antibody; Membrane type Matrix Metalloproteinase 6 antibody; Membrane-type matrix metalloproteinase 6 antibody; Membrane-type-6 matrix metalloproteinase antibody; MMP 25 antibody; MMP-25 antibody; MMP20 antibody; MMP20A antibody; MMP25 antibody; MMP25_HUMAN antibody; MMPL1 antibody; MT MMP 6 antibody; MT-MMP 6 antibody; MT6 MMP antibody; MT6-MMP antibody; MT6MMP antibody; MTMMP6 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human MMP25
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody