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Antibodies

BCR Antibody

Product Sizes
50 ul
£186.00
CSB-PA196525-50UL
100 ul
£334.00
CSB-PA196525-100UL
About this Product
SKU:
CSB-PA196525
Additional Names:
ALL antibody; bcr antibody; BCR/ABL FUSION GENE, INCLUDED antibody; BCR/FGFR1 chimera protein antibody; BCR/FGFR1 FUSION GENE, INCLUDED antibody; BCR/PDGFRA FUSION GENE, INCLUDED antibody; BCR_HUMAN antibody; BCR1 antibody; Breakpoint cluster region antibody; Breakpoint cluster region protein antibody; CML antibody; D22S11 antibody; D22S662 antibody; FGFR1/BCR chimera protein antibody; PHL antibody; Renal carcinoma antigen NY-REN-26 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human BCR
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody