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Antibodies

CDC25C (Ab-216) Antibody

Product Sizes
100 ul
£332.00
CSB-PA189566-100UL
About this Product
SKU:
CSB-PA189566
Additional Names:
CDC 25 antibody; Cdc 25C antibody; CDC25 antibody; CDC25C antibody; Cell division cycle 25 homolog C antibody; Cell division cycle 25C antibody; Cell division cycle 25C protein antibody; Dual specificity phosphatase Cdc25C antibody; M phase inducer phosphatase 3 antibody; M-phase inducer phosphatase 3 antibody; Mitosis inducer CDC25 antibody; MPIP3 antibody; MPIP3_HUMAN antibody; Phosphotyrosine phosphatase antibody; PPP1R60 antibody; protein phosphatase 1, regulatory subunit 60 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. Toyoshima-Morimoto F. et al. (2002) EMBO Rep. 3(4): 341-348. Ferguson AM. et al. (2005) Mol Cell Biol. 25(7): 2853-2860. Donzelli M. et al. (2003) EMBO Rep. 4(7): 671-677. Chen F. et al. (2002) Proc Natl Acad Sci U S A. 99(4): 1990-1995.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody