DNMT3L Antibody
Product Sizes
50 ul
£186.00
CSB-PA189054-50UL
100 ul
£334.00
CSB-PA189054-100UL
About this Product
- SKU:
- CSB-PA189054
- Additional Names:
- Cytosine 5 methyltransferase 3 like protein antibody; DNA (cytosine 5 ) methyltransferase 3 like antibody; DNA (cytosine-5)-methyltransferase 3-like antibody; DNA cytosine 5 methyltransferase 3 like protein antibody; DNA methyltransferase 3 like protein antibody; DNM3L_HUMAN antibody; Dnmt 3L antibody; Dnmt3l antibody; Human cytosine 5 methyltransferase 3 like protein antibody; MGC1090 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human DNMT3L
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DNMT3L-Antibody-11099382.html
