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Antibodies

HDAC7 Antibody, Biotin conjugated

Product Sizes
50 ug
£186.00
CSB-PA17899D0RB-50UG
100 ug
£334.00
CSB-PA17899D0RB-100UG
About this Product
SKU:
CSB-PA17899D0RB
Additional Names:
DKFZP586J0917 antibody; FLJ99588 antibody; HD 7a antibody; HD7 antibody; HD7a antibody; HDAC 7 antibody; HDAC 7A antibody; Hdac7 antibody; HDAC7_HUMAN antibody; HDAC7A antibody; Histone deacetylase 7 antibody; Histone deacetylase 7A antibody; OTTHUMP00000202813 antibody; OTTHUMP00000202814 antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
Host:
Rabbit
Immunogen:
Recombinant Human Histone deacetylase 7 protein (647-917AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody