TFAP2A Antibody
Product Sizes
100 ul
£332.00
CSB-PA178989-100UL
About this Product
- SKU:
- CSB-PA178989
- Additional Names:
- Activating enhancer binding protein 2 alpha antibody; Activating enhancer-binding protein 2-alpha antibody; Activator protein 2 antibody; AP 2 transcription factor antibody; AP 2alpha antibody; AP-2 antibody; AP-2 transcription factor antibody; AP2 antibody; AP2 Transcription Factor antibody; AP2-alpha antibody; AP2A_HUMAN antibody; AP2TF antibody; BOFS antibody; FLJ51761 antibody; TFAP 2 antibody; TFAP 2A antibody; TFAP2 antibody; TFAP2A antibody; Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha) antibody; Transcription factor AP-2-alpha antibody; Transcription factor AP2 alpha antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602. TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064. Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768. Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human AP-2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TFAP2A-Antibody-11084497.html
