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Antibodies

MEI1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA169796-50UL
100 ul
£334.00
CSB-PA169796-100UL
About this Product
SKU:
CSB-PA169796
Additional Names:
MEI1Meiosis inhibitor protein 1 antibody; Meiosis defective protein 1 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The predominant cause of spermatogenic arrest of meiosis is the failure of homologous chromosomes to accurately synapse. MEI1 (Meiosis inhibitor protein 1), also designated Meiosis defective protein 1, is a 1274 amino acid protein that is likely required for the formation of genetically programmed double-strand breaks, the first step in the initiation of meiosis. With predominant expression in testis, it is likely that defects of the gene encoding MEI1 results in male infertility. Interestingly, studies show that genetic variation in the MEI gene possibly predisposes European Americans but not Israeli men to infertility by meiotic arrest. Human MEI1 shares 79% sequence similarity with its mouse homolog. There are seven isoforms of MEI1 that are produced as a result of alternative splicing events.
Host:
Rabbit
Immunogen:
Fusion protein of Human MEI1
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody