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Antibodies

ANLN Antibody

Product Sizes
50 ul
£186.00
CSB-PA168510-50UL
100 ul
£334.00
CSB-PA168510-100UL
About this Product
SKU:
CSB-PA168510
Additional Names:
Actin binding protein scraps homolog Drosophila antibody; Actin binding protein anillin antibody; Actin-binding protein anillin antibody; Anillin actin binding protein antibody; anln antibody; ANLN_HUMAN antibody; DKFZp779A055 antibody; FSGS8 antibody; Scra antibody; Scraps antibody; Scraps homolog antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.
Host:
Rabbit
Immunogen:
Fusion protein of Human ANLN
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody