BAX Antibody
Product Sizes
100 ul
£332.00
CSB-PA167247-100UL
About this Product
- SKU:
- CSB-PA167247
- Additional Names:
- Apoptosis regulator BAX antibody; BAX antibody; Bax-protein antibody; BAX_HUMAN antibody; BAXA antibody; Baxdelta2G9 antibody; Baxdelta2G9omega antibody; Baxdelta2omega antibody; Bcl-2-like protein 4 antibody; BCL2 associated X protein antibody; BCL2 associated X protein omega antibody; BCL2 associated X protein transcript variant delta2 antibody; Bcl2-L-4 antibody; BCL2L4 antibody; membrane isoform alpha antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. Francesca Andriani, J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324. H Martinez-Valdez, J. Exp. Med., Mar 1996; 183: 971. Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312. Renren Wen, Mol. Cell. Biol., Jan 2001; 21: 678 - 689.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human Bax.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:BAX-Antibody-11084501.html
