ARL6IP1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA157358-50UL
100 ul
£334.00
CSB-PA157358-100UL
About this Product
- SKU:
- CSB-PA157358
- Additional Names:
- ADP ribosylation factor like 6 interacting protein antibody; ADP-ribosylation factor-like protein 6-interacting protein 1 antibody; Aip-1 antibody; Aip1 antibody; AR6P1_HUMAN antibody; ARL-6-interacting protein 1 antibody; ARL6 interacting protein 1 antibody; ARL6IP antibody; Arl6ip1 antibody; ARMER antibody; KIAA0069 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human ARL6IP1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ARL6IP1-Antibody-11100579.html
