H2AFX Antibody

Product Sizes

50 ug

£186.00

CSB-PA15429A0RB-50UG

100 ug

£334.00

CSB-PA15429A0RB-100UG

About this Product

SKU:: CSB-PA15429A0RB
Additional Names:: H2A histone family member X antibody; H2A histone family member X antibody; H2A.FX antibody; H2A.X antibody; H2a/x antibody; H2AFX antibody; H2AX antibody; H2AX_HUMAN antibody; Histone H2A.X antibody
Application:: ELISA, Immunohistochemistry
Buffer:: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:: Polyclonal
Extra Details:: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Host:: Rabbit
Immunogen:: Recombinant Human Histone H2AX protein (12-141AA)
Isotype:: IgG
Physical State:: Liquid
Purification:: Protein G Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:: Cusabio
Type:: Antibody: Polyclonal Antibody

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