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Antibodies

KNG1 Antibody, HRP conjugated

Product Sizes
50 ug
£186.00
CSB-PA14647B0RB-50UG
100 ug
£334.00
CSB-PA14647B0RB-100UG
About this Product
SKU:
CSB-PA14647B0RB
Additional Names:
Alpha-2-thiol proteinase inhibitor antibody; BDK antibody; BK antibody; Bradykinin antibody; Bradykinin included antibody; Fitzgerald factor antibody; FLAUJEAC FACTOR antibody; High molecular weight kininogen antibody; HMWK antibody; Ile-Ser-Bradykinin antibody; Kallidin I antibody; Kallidin II antibody; KNG antibody; KNG1 antibody; KNG1_HUMAN antibody; Low molecular weight growth-promoting factor antibody; WILLIAMS FACTOR antibody; Williams-Fitzgerald-Flaujeac factor antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
HRP
Extra Details:
Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Host:
Rabbit
Immunogen:
Recombinant Human Kininogen-1 protein (390-644AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody