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Antibodies

FAS Antibody

Product Sizes
100 ul
£332.00
CSB-PA146193-100UL
About this Product
SKU:
CSB-PA146193
Additional Names:
ALPS 1A antibody; ALPS1A antibody; APO 1 antibody; Apo 1 antigen antibody; APO 1 cell surface antigen antibody; Apo-1 antigen antibody; APO1 antibody; Apo1 antigen antibody; APO1 cell surface antigen antibody; Apoptosis antigen 1 antibody; Apoptosis mediating surface antigen FAS antibody; Apoptosis-mediating surface antigen FAS antibody; APT 1 antibody; APT1 antibody; CD 95 antibody; CD 95 antigen antibody; CD95 antibody; CD95 antigen antibody; Delta Fas antibody; Delta Fas/APO 1/CD95 antibody; Delta Fas/APO1/CD95 antibody; Fas (TNF receptor superfamily; member 6) antibody; FAS 1 antibody; FAS 827dupA antibody; Fas AMA antibody; Fas antibody; FAS Antigen antibody; Fas cell surface death receptor antibody; FAS1 antibody; FASLG receptor antibody; FASTM antibody; sFAS antibody; Surface antigen APO1 antibody; TNF receptor superfamily; member 6 antibody; TNFRSF 6 antibody; TNFRSF6 antibody; TNR6_HUMAN antibody; Tumor necrosis factor receptor superfamily member 6 antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). Hahne, M. et al. (1995) Int Immunol 7, 1381-6. Nagata, S. (1997) Cell 88, 355-65. Green, D.R. and Ferguson, T.A. (2001) Nat Rev Mol Cell Biol 2, 917-24.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.323~327 (E-N-S-N-F) derived from Human Fas .
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody