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Antibodies

CTDSP1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA131500-100UL
About this Product
SKU:
CSB-PA131500
Additional Names:
Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody; CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 antibody; CTD small phosphatase 1 antibody; CTDS1_HUMAN antibody; CTDSP1 antibody; NIF3 antibody; NLI IF antibody; NLI interacting factor 3 antibody; NLI-IF antibody; NLI-interacting factor 3 antibody; NLIIF antibody; Nuclear LIM interactor interacting factor 3 antibody; Nuclear LIM interactor-interacting factor 3 antibody; SCP1 antibody; Small C-terminal domain phosphatase 1 antibody; Small CTD phosphatase 1 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Marquet S., Mamm. Genome 11:755-762(2000). Yeo M., J. Biol. Chem. 278:26078-26085(2003). Hillier L.W., Nature 434:724-731(2005)
Host:
Rabbit
Immunogen:
Synthesized peptide derived from N-terminal of Human CTDSP1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody