DLC1 Antibody
Product Sizes
100 ul
£332.00
CSB-PA124374-100UL
About this Product
- SKU:
- CSB-PA124374
- Additional Names:
- ARHGAP 7 antibody; ARHGAP7 antibody; Deleted in liver cancer 1 antibody; Deleted in liver cancer 1 protein antibody; DLC 1 antibody; Dlc-1 antibody; DLC1 antibody; DLC1 Rho GTPase activating protein antibody; FLJ21120 antibody; HP antibody; HP protein antibody; KIAA1723 antibody; p122 RhoGAP antibody; RHG07_HUMAN antibody; Rho GTPase activating protein 7 antibody; Rho GTPase-activating protein 7 antibody; Rho type GTPase activating protein 7 antibody; Rho-type GTPase-activating protein 7 antibody; StAR related lipid transfer (START) domain containing 12 antibody; StAR related lipid transfer protein 12 antibody; StAR-related lipid transfer protein 12 antibody; STARD 12 antibody; StARD12 antibody; START domain containing protein 12 antibody; START domain-containing protein 12 antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. Yuan B.Z., Cancer Res. 58:2196-2199(1998). Nagase T., DNA Res. 7:347-355(2000). Wilson P.J., Hum. Mutat. 15:156-165(2000).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human RHG07.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DLC1-Antibody-11085223.html
