KITLG Antibody
Product Sizes
100 ul
£332.00
CSB-PA122514-100UL
About this Product
- SKU:
- CSB-PA122514
- Additional Names:
- C kit ligand antibody; C-kit ligand antibody; Ckit ligand antibody; DCUA antibody; DFNA69 antibody; DKFZp686F2250 antibody; familial progressive hyperpigmentation 2 antibody; FPH2 antibody; FPHH antibody; KIT ligand antibody; Kitl antibody; KITLG antibody; KL 1 antibody; KL1 antibody; Mast cell growth factor antibody; MGF antibody; MGF stem cell factor antibody; SCF antibody; SCF_HUMAN antibody; SF antibody; SHEP7 antibody; sKITLG antibody; Soluble KIT ligand antibody; Steel factor antibody; steel, mouse, homolog of antibody; Stem cell factor antibody; Stem cell factor precursor antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. Lu H.S., Clogston C.L., Wypych J. Arch. Biochem. Biophys. 298:150-158(1992)
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.265~269(E-K-E-R-E) derived from Human SCF.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:KITLG-Antibody-11083343.html
