GSK3B (Ab-9) Antibody
Product Sizes
100 ul
£332.00
CSB-PA120951-100UL
About this Product
- SKU:
- CSB-PA120951
- Additional Names:
- Glycogen Synthase Kinase 3 Beta antibody; Glycogen synthase kinase-3 beta antibody; GSK 3 beta antibody; GSK-3 beta antibody; GSK3B antibody; GSK3B_HUMAN antibody; GSK3beta isoform antibody; Serine/threonine-protein kinase GSK3B antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Fan G, et al. (2003) J Biol Chem. 278(52): 52432-52436.Barry FA, et al. (2003) FEBS Lett. 553(1-2): 173-178.Welsh, et al. (1996) Trends Cell Biol. 6: 274-279.Srivastava A K, et al. (1998) Mol Cell Biochem. 182: 135-141.Cross D. A, et al. (1995) Nature. 378: 785-789.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.7~11 (T-T-S-F-A) derived from Human GSK3b.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GSK3B-Ab-9-Antibody-11080500.html
