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Antibodies

NUMA1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA114858-100UL
About this Product
SKU:
CSB-PA114858
Additional Names:
Centrophilin stabilizes mitotic spindle in mitotic cells antibody; NMP 22 antibody; Nuclear matrix protein 22 antibody; Nuclear mitotic apparatus protein 1 antibody; Nuclear mitotic apparatus protein antibody; NUMA 1 antibody; NUMA antibody; NuMA protein antibody; NUMA1 antibody; NUMA1_HUMAN antibody; SP H antigen antibody; SP-H antigen antibody; Structural nuclear protein antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions. Yang C.H., J. Cell Biol. 116:1303-1317(1992). Compton D.A., J. Cell Biol. 116:1395-1408(1992). Maekawa T., J. Cell Sci. 105:589-600(1993).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human NUMA1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody