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Antibodies

LCAT Antibody, Biotin conjugated

Product Sizes
50 ug
£186.00
CSB-PA11369D0RB-50UG
100 ug
£334.00
CSB-PA11369D0RB-100UG
About this Product
SKU:
CSB-PA11369D0RB
Additional Names:
LCAT antibody; LCAT_HUMAN antibody; Lecithin cholesterol acyltransferase antibody; Lecithin-cholesterol acyltransferase antibody; Phosphatidylcholine sterol acyltransferase antibody; Phosphatidylcholine-sterol acyltransferase antibody; Phospholipid cholesterol acyltransferase antibody; Phospholipid-cholesterol acyltransferase antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.
Host:
Rabbit
Immunogen:
Recombinant Human Phosphatidylcholine-sterol acyltransferase protein (25-433AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody