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Antibodies

PLA2G2A Antibody

Product Sizes
50 ug
£186.00
CSB-PA11209A0RB-50UG
100 ug
£334.00
CSB-PA11209A0RB-100UG
About this Product
SKU:
CSB-PA11209A0RB
Additional Names:
EC 3.1.1.4 antibody; GIIC sPLA2 antibody; Group IIA phospholipase A2 antibody; membrane associated antibody; Modifier of MIN 1 mouse homolog antibody; MOM1 antibody; Non-pancreatic secretory phospholipase A2 antibody; NPS PLA2 antibody; NPS-PLA2 antibody; PA2GA_HUMAN antibody; Phosphatidylcholine 2-acylhydrolase 2A antibody; Phosphatidylcholine 2acylhydrolase antibody; Phospholipase A2 antibody; Phospholipase A2 group IIA (platelets, synovial fluid) antibody; Phospholipase A2 membrane associated antibody; Phospholipase A2 polypeptide B antibody; Phospholipase A2 synovial antibody; PLA2 antibody; PLA2B antibody; PLA2G2A antibody; PLA2L antibody; PLA2S antibody; PLAS1 antibody; RASF A antibody; sPLA2 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Host:
Rabbit
Immunogen:
Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody