ANO1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA110575-50UL
100 ul
£334.00
CSB-PA110575-100UL
About this Product
- SKU:
- CSB-PA110575
- Additional Names:
- ANO 1 antibody; ANO1 antibody; ANO1_HUMAN antibody; Anoctamin 1 antibody; Anoctamin 1 calcium activated chloride channel antibody; Anoctamin-1 antibody; Anoctamin1 antibody; Ca2+ activated Cl- channel antibody; Calcium Activated Chloride Channel antibody; Discovered on gastrointestinal stromal tumors protein 1 antibody; DOG 1 antibody; DOG1 antibody; FLJ10261 antibody; Membrane protein antibody; Oral cancer overexpressed 2 antibody; Oral cancer overexpressed protein 2 antibody; ORAOV 2 antibody; ORAOV2 antibody; TAOS 2 antibody; TAOS2 antibody; TMEM 16A antibody; TMEM16A antibody; Transmembrane protein 16A (eight membrane spanning domains) antibody; Transmembrane protein 16A antibody; Tumor amplified and overexpressed sequence 2 antibody; Tumor-amplified and overexpressed sequence 2 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human ANO1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ANO1-Antibody-11103767.html
