APLF (Ab-116) Antibody
Product Sizes
100 ul
£332.00
CSB-PA109959-100UL
About this Product
- SKU:
- CSB-PA109959
- Additional Names:
- 2010301N04Rik antibody; AI452191 antibody; Aplf antibody; APLF_HUMAN antibody; Aprataxin and PNK-like factor antibody; Apurinic-apyrimidinic endonuclease APLF antibody; C2orf13 antibody; PNK and APTX like FHA protein antibody; PNK and APTX-like FHA domain-containing protein antibody; RGD1565557 antibody; XIP1 antibody; XRCC1 interacting protein 1 antibody; XRCC1-interacting protein 1 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. Saunders W.S., J. Cell Sci. 104:573-582(1993). Ye Q., J. Biol. Chem. 271:14653-14656(1996). Ye Q., J. Biol. Chem. 272:14983-14989(1997).
- Host:
- Rabbit
- Immunogen:
- Synthesized non-phosphopeptide derived from Human APLF around the phosphorylation site of serine 116 (R-N-S(p)-Q-V).
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:APLF-Ab-116-Antibody-11084445.html
