MEN1 Antibody
Product Sizes
100 ul
£332.00
CSB-PA108807-100UL
About this Product
- SKU:
- CSB-PA108807
- Additional Names:
- MEA 1 antibody; MEA1 antibody; MEN 1 antibody; Men1 antibody; MEN1_HUMAN antibody; Menin antibody; Multiple Endocrine Adenomatosis 1 antibody; Multiple Endocrine Neoplasia 1 antibody; SCG 2 antibody; SCG2 antibody; Suppressor Candidate Gene 2 antibody; Wermer syndrome antibody; ZES antibody; Zollinger Ellison Syndrome antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression By similarity. May be involved in DNA repair. Chandrasekharappa S.C., Science 276:404-407(1997). Jin S., Cancer Res. 63:4204-4210(2003). Schnepp R.W., Cancer Res. 64:6791-6796(2004).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human MEN1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MEN1-Antibody-11085479.html
