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Antibodies

DOK1 (Ab-398) Antibody

Product Sizes
100 ul
£332.00
CSB-PA107033-100UL
About this Product
SKU:
CSB-PA107033
Additional Names:
Docking protein 1 62kD antibody; Docking protein 1 antibody; DOK 1 antibody; DOK1 antibody; DOK1_HUMAN antibody; Downstream of tyrosine kinase 1 antibody; p62(dok) antibody; P62DOK antibody; pp62 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. Michael J. Wick,et,al. (2001) J. Biol. Chem; 276: 42843 - 42850. Paul D. Simoncic, et,al. (2006) Mol. Cell. Biol; 26: 4149 - 4160. Nadia Dub
Host:
Rabbit
Immunogen:
Peptide sequence around aa.396~400 (P-I-Y-D-E) derived from Human p62Dok.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody