GNL3L Antibody
Product Sizes
100 ul
£332.00
CSB-PA106099-100UL
About this Product
- SKU:
- CSB-PA106099
- Additional Names:
- GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. Ota T., Nat. Genet. 36:40-45(2004). Ross M.T., Nature 434:325-337(2005). The MGC Project Team; Genome Res. 14-2121-2127(2004).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human GNL3L.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GNL3L-Antibody-11085936.html
