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Antibodies

CENPA Antibody

Product Sizes
100 ul
£332.00
CSB-PA097091-100UL
About this Product
SKU:
CSB-PA097091
Additional Names:
CENP A antibody; CENP-A antibody; cenpa antibody; CENPA_HUMAN antibody; Centromere autoantigen A antibody; Centromere protein A 17kDa antibody; Centromere protein A antibody; Histone H3 like centromeric protein A antibody; Histone H3-like centromeric protein A antibody
Application:
ELISA, Immunohistochemistry
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro). Sullivan K.F., J. Cell Biol. 127:581-592(1994). Hillier L.W., Nature 434:724-731(2005). Shelby R.D., J. Cell Biol. 136:501-513(1997).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human CENPA.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody