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Antibodies

CDH23 Antibody

Product Sizes
100 ul
£332.00
CSB-PA094215-100UL
About this Product
SKU:
CSB-PA094215
Additional Names:
CDH23 antibody; KIAA1774 antibody; KIAA1812 antibody; UNQ1894/PRO4340Cadherin-23 antibody; Otocadherin antibody
Application:
ELISA, Immunohistochemistry
Buffer:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Clonality:
Polyclonal
Extra Details:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to residues near the C terminal of Human pan-cadherin
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody