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Antibodies

DSP Antibody

Product Sizes
50 ul
£186.00
CSB-PA093388-50UL
100 ul
£334.00
CSB-PA093388-100UL
About this Product
SKU:
CSB-PA093388
Additional Names:
250/210 kDa paraneoplastic pemphigus antigen antibody; DCWHKTA antibody; Desmoplakin (DPI DPII) antibody; Desmoplakin antibody; Desmoplakin I antibody; Desmoplakin II antibody; DESP_HUMAN antibody; DP antibody; DP I antibody; DP II antibody; DPI antibody; DPII antibody; DSP antibody; KPPS2 antibody; PPKS 2 antibody; PPKS2 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human DSP
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody