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Antibodies

MLH1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA091025-50UL
100 ul
£334.00
CSB-PA091025-100UL
About this Product
SKU:
CSB-PA091025
Additional Names:
COCA 2 antibody; COCA2 antibody; DNA mismatch repair protein Mlh1 antibody; FCC 2 antibody; FCC2 antibody; hMLH 1 antibody; hMLH1 antibody; HNPCC 2 antibody; HNPCC antibody; HNPCC2 antibody; MGC5172 antibody; MLH 1 antibody; MLH1 antibody; MLH1_HUMAN antibody; MutL homolog 1 (E. coli) antibody; MutL homolog 1 antibody; MutL homolog 1 colon cancer nonpolyposis type 2 antibody; MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody; MutL protein homolog 1 antibody; MutL, E. coli, homolog of, 1 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Host:
Rabbit
Immunogen:
Fusion protein of Human MLH1
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody